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最終更新日 2019/2/17 1:12:28
Correction: Potassium is a trigger for conformational change in the fusion spike of an enveloped RNA virus. [Additions and Corrections]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
VOLUME 293 (2018) PAGES 9937?9944Drs. Fontana, Mankouri, and Barr should all have been listed as corresponding authors. Dr. Fontana's contact information is as follows: Tel.: 44-113-3434170; E-mail: J.Fontana@leeds.ac.uk. Dr. Mankouri's contact information is as follows: Tel.: 44-113-3435646; E-mail: J.Mankouri@leeds.ac.uk.
Differential S-palmitoylation of the human and rodent {beta}3-adrenergic receptors [Cell Biology]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
With few reported exceptions, G protein?coupled receptors (GPCRs) are modified by Cys palmitoylation (S-palmitoylation). In multiple GPCRs, S-palmitoylation targets a canonical site within the C-termi ...
Metabolic fingerprinting for diagnosis of fibromyalgia and other rheumatologic disorders [Molecular Bases of Disease]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
Diagnosis and treatment of fibromyalgia (FM) remains a challenge owing to the lack of reliable biomarkers. Our objective was to develop a rapid biomarker-based method for diagnosing FM by using vibrat ...
Muscle A-kinase-anchoring protein-{beta}-bound calcineurin toggles active and repressive transcriptional complexes of myocyte enhancer factor 2D [Cell Biology]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
Myocyte enhancer factor 2 (MEF2) transcription factors are key regulators of the development and adult phenotype of diverse tissues, including skeletal and cardiac muscles. Controlled by multiple post ...
Structure-based switch of regioselectivity in the flavin-dependent tryptophan 6-halogenase Thal [Protein Structure and Folding]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
Flavin-dependent halogenases increasingly attract attention as biocatalysts in organic synthesis, facilitating environmentally friendly halogenation strategies that require only FADH2, oxygen, and hal ...
Regulation of erythrocyte Na+/K+/2Cl- cotransport by an oxygen-switched kinase cascade [Signal Transduction]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
Many erythrocyte processes and pathways, including glycolysis, the pentose phosphate pathway (PPP), KCl cotransport, ATP release, Na+/K+-ATPase activity, ankyrin?band 3 interactions, and nitric oxide ...
The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial {beta}1-adrenergic receptor expression and signaling [Cell Biology]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
Reversible ubiquitination of G protein?coupled receptors regulates their trafficking and signaling; whether deubiquitinases regulate myocardial ?1-adrenergic receptors (?1ARs) is unknown. We report th ...
Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1 [Molecular Bases of Disease]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
Chronic benzene exposure is associated with hematotoxicity and the development of aplastic anemia and leukemia. However, the signaling pathways underlying benzene-induced hematotoxicity remain to be d ...
A serine in the first transmembrane domain of the human E3 ubiquitin ligase MARCH9 is critical for down-regulation of its protein substrates [Immunology]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
The membrane-associated RING-CH (MARCH) family of membrane-bound E3 ubiquitin ligases regulates the levels of cell-surface membrane proteins, many of which are involved in immune responses. Although t ...
Transcription factor TFAP2B up-regulates human corneal endothelial cell-specific genes during corneal development and maintenance [Cell Biology]
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
from Journal of Biological Chemistry current issue (2019/2/14 19:12:50)
The corneal endothelium, which originates from the neural crest via the periocular mesenchyme (PM), is crucial for maintaining corneal transparency. The development of corneal endothelial cells (CECs) ...
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