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最終更新日 2019/11/19 20:34:41
Expression of Concern: Tumor suppressor SMAR1 activates and stabilizes p53 through its arginine-serine-rich motif. [Expressions of Concern]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
VOLUME 280 (2005) PAGES 16019?16029The publisher of the Journal of Biological Chemistry is issuing an Expression of Concern to inform readers that credible concerns have been raised regarding some of the data and conclusions in the article listed above. The Journal of Biological Chemistry will provide additional information as it becomes available.
Correction: Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma. [Additions and Corrections]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
VOLUME 294 (2019) PAGES 11286?11296Throughout the text, the abbreviations ?EWS-FLI1? and ?EWS-FLI3? refer to EWS-FLI1, type 1 and EWS-FLI1, type 3, respectively. These are EWS-FLI1 fusion proteins tha ...
Control of cellular responses to mechanical cues through YAP/TAZ regulation [Cell Biology]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
To perceive their three-dimensional environment, cells and tissues must be able to sense and interpret various physical forces like shear, tensile, and compression stress. These forces can be generate ...
The biosynthetic diversity of the animal world [Enzymology]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
Secondary metabolites are often considered within the remit of bacterial or plant research, but animals also contain a plethora of these molecules with important functional roles. Classical feeding st ...
How organic chemistry became one of UCLA's most popular classes [ASBMB Award Articles]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
Organic chemistry has a bad reputation, despite having a tremendous impact on our everyday lives. It has remained a notorious ?weed-out? class for decades?striking fear in the hearts of students?and h ...
Hypoxia-inducible gene domain 1 proteins in yeast mitochondria protect against proton leak through complex IV [Membrane Biology]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
Hypoxia-inducible gene domain 1 (HIGD1) proteins are small integral membrane proteins, conserved from bacteria to humans, that associate with oxidative phosphorylation supercomplexes. Using yeast as a ...
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens [Enzymology]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
WT P53-Induced Phosphatase 1 (WIP1) is a member of the magnesium-dependent serine/threonine protein phosphatase (PPM) family and is induced by P53 in response to DNA damage. In several human cancers, ...
Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition [Microbiology]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
Methylation of the small ribosome subunit rRNA in the ribosomal decoding center results in exceptionally high-level aminoglycoside resistance in bacteria. Enzymes that methylate 16S rRNA on N7 of nucl ...
Manganese co-localizes with calcium and phosphorus in Chlamydomonas acidocalcisomes and is mobilized in manganese-deficient conditions [Plant Biology]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
Exposing cells to excess metal concentrations well beyond the cellular quota is a powerful tool for understanding the molecular mechanisms of metal homeostasis. Such improved understanding may enable ...
A dual-chain assembly pathway generates the high structural diversity of cell-wall polysaccharides in Lactococcus lactis [Glycobiology and Extracellular Matrices]
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
from Journal of Biological Chemistry current issue (2019/11/15 17:06:23)
In Lactococcus lactis, cell-wall polysaccharides (CWPSs) act as receptors for many bacteriophages, and their structural diversity among strains explains, at least partially, the narrow host range of t ...
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