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タイトル: Quantitative analysis of the effect of docetaxel-induced edema on quality of life in patients with breast cancer and related factors: a prospective cohort study著者: Izawa, Tomoko; Kobayashi, Ami; Kawashima, Masahiro; Kawaguchi-Sakita, Nobuko; Nakakura, Akiyoshi; Kataoka, Yuki; Shide, Kenichiro; Mori, Yukiko; Yamazaki, Kazuhiro; Toi, Masakazu; Arao, Harue抄録: Background: Systemic edema is an adverse effect of docetaxel chemotherapy and causes distress to patients, including those receiving this agent for breast cancer. However, its characteristics and factors related to its effect on quality of life (QoL) have not been adequately investigated. In this study, we assessed systemic edema quantitatively, explored related factors, and evaluated QoL in patients receiving docetaxel for breast cancer. Methods: The study had a prospective cohort design and included 37 patients with no known history of swelling who were treated with docetaxel between September 2019 and April 2 ...

2024年度の利用報告は、全国の約1,800校（大学は学部単位）に依頼させていただきます。 対象校の設置者のご担当者様には、3月20日頃までにSARTRASから依頼状をお送りいたします。また、併せてメール等でもご連絡を差し上げる予定ですので、ご確認のほどお願い申し上げます。ご報告をお願いする期間は、各校とも原則としてSARTRASから指定させていただく1か月間です。 利用報告は、全国の教育機関設置者の皆さまからお支払いいただきました授業目的公衆送信補償金を、授業で公衆送信された著作物等の権利者へお届けするための大変重要な資料となります。対象校となられる皆さまにはご負担をお掛けいたしますが、何卒ご理解、ご協力を賜りますようお願い申し上げます。 なお、調査精度の確保のため、追加で対象校を選定して4月中 ...

タイトル: Treatment of hepatitis in ex-biomedical chimpanzees at a Japanese sanctuary thanks to support from the general public著者: Hirata, Satoshi

タイトル: Regioselective anti-Silyllithiation of Propargylic Amines著者: Sato, Tomohiko; Karad, Somnath N.; Shimokawa, Jun; Yorimitsu, Hideki抄録: The regioselective anti-silyllithiation of propargylic amines is developed to facilitate the efficient synthesis of alkenylsilanes. This reaction generates an alkenyllithium intermediate that is stabilized by the formation of a five-membered cyclic structure through intramolecular coordination of the nitrogen functional group. Upon subsequent treatment with an electrophile, the alkenyllithium intermediate is further functionalized to afford tetrasubstituted allylic amines bearing a β-silicon substituent.

タイトル: CT number calibration audit in photon radiation therapy著者: Nakao, Minoru; Ozawa, Shuichi; Miura, Hideharu; Yamada, Kiyoshi; Hayata, Masahiro; Hayashi, Kosuke; Kawahara, Daisuke; Nakashima, Takeo; Ochi, Yusuke; Okumura, Takuro; Kunimoto, Haruhide; Kawakubo, Atsushi; Kusaba, Hayate; Nozaki, Hiroshige; Habara, Kosaku; Tohyama, Naoki; Nishio, Teiji; Nakamura, Mitsuhiro; Minemura, Toshiyuki; Okamoto, Hiroyuki; Ishikawa, Masayori; Kurooka, Masahiko; Shimizu, Hidetoshi; Hotta, Kenji; Saito, Masahide; Nakano, Masahiro; Tsuneda, Masato; Nagata, Yasushi抄録: Background: Inadequate computed tomography (CT) number calibration curves affect dose calculation accuracy. Although CT number calibration curves registered in treatment planning systems (TPSs) should be consistent with human tissues, it is unclear whether adequate CT number calibration is performed because CT number calibration curves have not been assessed for various types of CT number calibration phantoms and TPSs.; P ...

タイトル: Continuous inhalation of essential oil increases gray matter volume著者: Kokubun, Keisuke; Nemoto, Kiyotaka; Yamakawa, Yoshinori抄録: Research into the health benefits of scents is on the rise. However, little is known about the effects of continuous inhalation, such as wearing scents on clothing, on brain structure. Therefore, in this study, an intervention study was conducted on a total of 50 healthy female people, 28 in the intervention group and 22 in the control group, asking them to wear a designated rose scent on their clothes for a month. The effect of continuous inhalation of essential oil on the gray matter of the brain was measured by calculating changes in brain images of participants taken before and after the intervention using Magnetic Resonance Imaging (MRI). The results showed that the intervention increased the gray matter volume (GMV) of the whole brain and posterior cingulate cortex (PCC) subregion. On the other hand, the GMV of the amygdala and or ...