リンク集 RSS/ATOM 記事

Tens of Thousands Join 2023 Library of Congress National Book Festival Tens of thousands of book lovers joined the Library of Congress National Book Festival in person on Aug. 12 at the Washington Convention Center, including capacity crowds on numerous stages. Videos of select stages are now available , and individual presentations will be made available on demand on the festival’s website beginning the week of Aug. 21. Click here for more information . You are subscribed to Latest News from the Library of Congress.

2023年7月の月間アクセスランキングを掲載しました。

タイトル: Imiquimod for Cervical and Vaginal Intraepithelial Neoplasia A Systematic Review and Meta-analysis著者: Inayama, Yoshihide; Takamatsu, Shiro; Hamanishi, Junzo; Mizuno, Kayoko; Horinouchi, Noboru; Yamanoi, Koji; Taki, Mana; Murakami, Ryusuke; Yamaguchi, Ken; Kosaka, Kenzo; Efthimiou, Orestis; Kawakami, Koji; Furukawa, Toshiaki A.; Mandai, Masaki抄録: OBJECTIVE: To evaluate the treatment efficacy and the risk of adverse events of imiquimod for cervical intraepithelial neoplasia (CIN) and vaginal intraepithelial neoplasia (VAIN), compared with placebo or no intervention. DATA SOURCES: We searched Cochrane, PubMed, ISRCTN registry, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform up to November 23, 2022. METHODS OF STUDY SELECTION: We included randomized controlled trials and prospective nonrandomized studies with control arms that investigated the efficacy of imiquimod for histologically confirmed CIN or VAIN. The prim ...

タイトル: Synthesis of Benzo[c]azepine-1,3(2H)-diones via C-H Alkylation/Cyclization with α,β-Unsaturated Acyl Fluorides著者: Hosoi, Satoko; Hirata, Yuki; Kurihara, Takumaru; Kojima, Masahiro; Yoshino, Tatsuhiko; Matsunaga, Shigeki抄録: Transition-metal-catalyzed directed C−H functionalization reactions are a powerful method to construct N-heterocycles. However, compared to the formation of five- and six-membered rings, that of seven-membered rings has been much less explored. Here, the synthesis of benzo[c]azepine-1, 3(2H)-diones is described, which are benzene-fused seven-membered imides, from hydroxamates and α, β-unsaturated acyl fluorides via C−H activation using a Cp[*]Rh(III) catalyst. Under mild reaction conditions, this reaction affords benzo[c]azepine-1, 3(2H)-diones that bear a substituent at the 5-position.

タイトル: メルケル政権期の福祉国家変容 --社会的投資、福祉排外主義、社会的気候政策の観点から--著者: 近藤, 正基記述: 秋月謙吾教授追悼号

「科研費ウェブサイトコレクション」を更新しました。

2023年8月の特集「New Archived Websites」を掲載しました。

【電話番号】0242-55-1122（代表）

タイトル: Enantioselective Synthesis of 1,2-Benzothiazine 1-Imines via Ru[II]/Chiral Carboxylic Acid-Catalyzed C−H Alkylation/Cyclization著者: Huang, Long-Tao; Kitakawa, Yuta; Yamada, Kodai; Kamiyama, Futa; Kojima, Masahiro; Yoshino, Tatsuhiko; Matsunaga, Shigeki抄録: Sulfondiimines are diaza-analogues of sulfones with a chiral sulfur center. Compared to sulfones and sulfoximines, their synthesis and transformations have so far been studied to a lesser extent. Here, we report the enantioselective synthesis of 1, 2-benzothiazine 1-imines, i.e., cyclic sulfondiimine derivatives from sulfondiimines and sulfoxonium ylides via C−H alkylation/cyclization reactions. The combination of [Ru(p-cymene)Cl₂]₂ and a newly developed chiral spiro carboxylic acid is key to achieving high enantioselectivity.

本研究所の夏季一斉休業に伴い、以下の通り、 IRDB/JaLC準会員の申請・問い合わせ窓口を休止致します。 ・窓口休止期間：2023年8月11日（金） - 8月15日（火） お問い合わせ等への返信は、8月16日（水）以降となります。 なお、各サービス自体は上記期間中も停止いたしません。