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短期大学部地域創成学科は日本遺産「一本の水路」プロモーション協議会から一本の水路ブランド認証を受けました。 同協議会は、明治時代に安積疏水を切り拓いた大久保利通や地元有志らの開拓者精神を受け継ぎ広めようと、挑戦・多様性・共生のイメージに深く関連づけられる優れた商品や優れた取り組みを行っている団体をブランド認証しています。 地域創成学科は、地域創成プロジェクト活動として、安積開拓や一本の水路に関連したノベルティグッズの制作、ゆかりの地を巡るコースを考え案内する「駅長おススメの小さな旅」などを実施。短期大学部が文化庁の日本遺産サポーター大学の登録第１号になる評価を受けました。 こうした活動がブランド認証され、今後の取り組みや事業を行う際に一本の水路のロゴを取り入れた ...

タイトル: Mechanistic elucidation of human pancreatic acinar development using single-cell transcriptome analysis on a human iPSC differentiation model.著者: Mima, Atsushi; Kimura, Azuma; Ito, Ryo; Hatano, Yu; Tsujimoto, Hiraku; Mae, Shin-Ichi; Yamane, Junko; Fujibuchi, Wataru; Uza, Norimitsu; Toyoda, Taro; Seno, Hiroshi; Osafune, Kenji抄録: Few effective treatments have been developed for intractable pancreatic exocrine disorders due to the lack of suitable disease models using human cells. Pancreatic acinar cells differentiated from human induced pluripotent stem cells (hiPSCs) have the potential to solve this issue. In this study, we aimed to elucidate the developmental mechanisms of pancreatic exocrine acinar lineages to establish a directed differentiation method for pancreatic acinar cells from hiPSCs. hiPSC-derived pancreatic endoderm cells were spontaneously differentiated into both pancreatic exocrine and endocrine tissues by implantation into the renal subcapsular spa ...

タイトル: Retention of locally injected human iPS cell-derived cardiomyocytes into the myocardium using hydrolyzed gelatin著者: Iida, Jun; Kotani, Kazuki; Murata, Kozue; Hakamada, Keisuke; Maihemuti, Wusiman; Mandai, Yoshinobu; Hiraoka, Yosuke; Minatoya, Kenji; Masumoto, Hidetoshi抄録: This study explored the impact of hydrolyzed gelatin (HG) concentration on the retention and therapeutic efficacy of human iPS cell-derived cardiomyocytes (hiPSC-CMs) when injected into the myocardium. The solubility of HG allows precise control over its concentration, influencing the distribution and leakage of injected solutions, which may affect therapeutic outcomes. Using both ex vivo and in vivo rat models, we investigated how varying HG concentrations affect the retention of solution and diffusion within the myocardium. In ex vivo static rat hearts, 10% HG minimized leakage but allowed significant diffusion. However, in pulsating in vivo hearts, 20% HG provided the best retention. In a rat ...

タイトル: Sleeve basal segmentectomy with pulmonary artery division for lung cancer: how to do it.著者: Yutaka, Yojiro; Ryo, Taiki; Date, Hiroshi抄録: Sleeve segmentectomy was originally developed to preserve the lung volume in patients who were unable to tolerate lobectomy. We herein report an immunocompromised patient with potentially curable peripheral squamous cell carcinoma in whom sleeve basal segmentectomy was performed for a 1.8-cm tumor with endobronchial growth that occluded B7 and invaded the inlet of the middle lobar bronchus and B6. To provide sufficient surgical exposure for complex double-barrel reconstruction after segmentectomy, A6 was divided and reconstructed after the anastomosis was complete. This technique may be applicable to other peripheral bronchial reconstructions to minimize blood flow disruption to bronchial anastomosis.

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