リンク集 RSS/ATOM 記事

タイトル: Sustainability of cities under declining population and decreasing distance frictions: The case of Japan著者: Mori, Tomoya; Murakami, Daisuke抄録: This study develops a statistical model that integrates economic agglomeration theory and power-law distributions of city sizes to project future population distribution on 1-km grid cells. We focus on Japan – a country at the forefront of rapid population decline. Drawing on official population projections and empirical patterns from past urban evolution in response to the development of high-speed rail and highway networks, we examine how ongoing demographic contraction and expected reductions in distance frictions may reshape urban geography. Our analysis suggests that urban economies will consolidate around fewer and larger cities, each of which will experience a flattening of population density as the decentralization of urban populations accelerates, while rural areas are expected to experience further depopulation ...

タイトル: 岡田節男氏へのインタビュー --2023年12月22日実施--著者: 鈴木, 真奈記述: 本インタビュー実施形式はZoomを使用したビデオと音声によるWebミーティングである．総実施時間(録画時間)は約2時間58分であるが, その内の(自己紹介や休憩時間などを取り除いた)約2時間15分を文字起こしの上, 可読性のために表現を改めている.

タイトル: 財団法人理化学研究所仁科芳雄研究室における女性研究従事者についての予備的研究著者: 伊藤, 憲二記述: 本稿は2025年1月18日広島叡啓大学において行われたワークショップ「日本における女性科学者の誕生」において発表した内容に基づく．; 本稿の作成にあたっては，校正時における表現の統一などに生成系AIを使用した．

タイトル: Aldh2 and the tumor suppressor Trp53 play important roles in alcohol‑induced squamous feld cancerization著者: Kondo, Yuki; Ohashi, Shinya; Katada, Chikatoshi; Nakai, Yukie; Yamamoto, Yoshihiro; Tamaoki, Masashi; Kikuchi, Osamu; Yamada, Atsushi; Hirohashi, Kenshiro; Mitani, Yosuke; Kataoka, Shigeki; Saito, Tomoki; Nguyen Vu, Trang H.; Kondo, Tomohiro; Uneno, Yu; Sunami, Tomohiko; Yokoyama, Akira; Matsubara, Junichi; Matsuda, Tomonari; Naganuma, Seiji; Oryu, Kohei; Flashner, Samuel; Shimonosono, Masataka; Nakagawa, Hiroshi; Muto, Manabu抄録: BACKGOROUND: Field cancerization defined by multiple development of squamous cell carcinomas (SCCs) in upper aerodigestive tract was explained by excessive alcohol intake. A dysfunctional mitochondrial aldehyde dehydrogenase 2 (Aldh2) delays the clearance of acetaldehyde, a genotoxic alcohol metabolite, and increases SCC risks. TP53 plays key roles in squamous carcinogenesis. However, the mechanism of alcohol-mediated squamous fie ...

タイトル: Microfluidics-guided fluorescent nanodiamond assembly method for highly sensitive thermometry著者: Saikawa, Keita; Zetsu, Masaya; Ueshima, Daiki; Shikama, Taiichi; Kamei, Ken-ichiro; Tabata, Osamu; Hirai, Yoshikazu抄録: Fluorescent nanodiamonds (FNDs) with nitrogen vacancy centers (NVCs) show promise for use as thermometers owing to their unique physicochemical and optical properties. FND-based thermometry has been steadily developing and is now transitioning into the practical application phase. Various approaches have been proposed for FND assembly, which is a key process for temperature mapping applications. However, the assembly of high-sensitivity FND thermometers remains challenging because it requires the fabrication of three-dimensionally aggregated FNDs across the target area to generate a strong fluorescence signal. To overcome this drawback, we aimed to enable the microfluidics-guided assembly of FNDs to enhance the sensitivity of FND-based thermometry. Spe ...

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