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タイトル: Tadalafil use is associated with a lower incidence of Type 2 diabetes in men with benign prostatic hyperplasia: A population-based cohort study著者: Takayama, Atsushi; Yoshida, Satomi; Kawakami, Koji抄録: BACKGROUND: Tadalafil, commonly prescribed for benign prostatic hyperplasia (BPH), may benefit patients with Type 2 diabetes mellitus (T2DM) for glycemic markers and complications. However, the association between the long-term use of tadalafil and the incidence of T2DM has not been investigated. METHODS: We emulated a target trial of tadalafil use (5 mg/day) and the risk of T2DM using a population-based claims database in Japan. Patients who initiated tadalafil or alpha-blockers for BPH and had no history of diabetes diagnosis, no dispensing of glucose-lowering drugs, and no history of hemoglobin A1c levels of ≥6.5% (47–48 mmol/mol) were included. The primary outcome was the incidence of T2DM. Pooled logistic regression was used to estimate adjusted risk ratios ...

以下の資料と情報を紹介した。1 図書『皇室事典 令和版』（皇室事典編集委員会編著 KADOKAWA 2019） p37「奈良時代以前の命名法」 「古くは命名の次第などは定かでない。（中略）しかし古くは皇子の生誕地や、養育に与った地域・集団などの名称、兄弟関係にちなんだ例が少なくない。（中略）乳母の名にちなむものに、32 崇峻天皇の泊瀬部、38 天智天皇の葛城」とあり。『天智天皇』（森公章著 吉川弘文館 2016） p12-15 葛城の地名などについて説明あり。 p15「命名の由来と中大兄の語義」 「天智＝葛城皇子の命名は、「葛城宮」のような独自の王宮があったのではなく、雄族葛城氏とは系譜を異にし、葛城に拠点をもつ中小豪族、葛城国造や葛城県主とつながる士族や葛木稚犬養氏などが、乳母として資養を担当したので、乳母の氏族名に ...

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