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9月23日2017ふくしま環境フェスタを開催します

Treasury disputes Moody’s gloomy outlook for public finances

Statement from FDA Commissioner Scott Gottlieb, M.D., on FDA?s immediate steps to respond to Hurricane Maria and ongoing recovery efforts related to Hurricane?s Harvey and Irma

Aegerion Pharmaceuticals Inc. agreed to plead guilty in the United States District Court for the District of Massachusetts to two misdemeanor counts of violating the Federal Food, Drug, and Cosmetic Act (FD&C Act) involving the introduction of misbranded Juxtapid (lomitapide) into interstate commerce.

内容：牛たん土産品・食肉類の パック・袋詰め等の軽作業 時給 ：８５０円 資格 ：不問（学歴・国籍等） 勤務 ：(フルタイム) 8:30〜17:00 (午前パート) 8:30〜12:30 (午後パート)13:00〜17:00 休日 ：日曜・祝日・水曜日 (規定休日カレンダーによる) 待遇 ：社会保険、失業保険、車通勤 可、制服貸与、自家用車通勤 費支給（規定による） 応募 ：電話連絡の上、履歴書持参 ください ※正社員も同時募集(委細面談) ＜地下鉄卸町駅徒歩３分＞ 〒984-0015 仙台市若林区卸町１−５−１１株式会社 トーチクTEL０２２−２３９−４１２９（担当中澤）

by Floor Holvast, Btissame Massoudi, Richard C. Oude Voshaar, Peter F. M. Verhaak Background Late-life depression is most often treated in primary care, and it usually coincides with chronic somatic diseases. Given that antidepressants contribute to polypharmacy in these patients, and potentially to interactions with other drugs, non-pharmacological treatments are essential. In this systematic review and meta-analysis, we aimed to present an overview of the non-pharmacological treatments available in primary care for late-life depression. Method The databases of PubMed, PsychINFO, and the Cochrane Central Register of Controlled Trials were systematically searched in January 2017 with combinations of MeSH-terms and free text words for “general practice,” “older adults,” “depression,” and “non-pharmacological treatment”. All studies with empirical data concerning adults aged 60 years or older were included, and the results were stratified by primary care, and community setting. ...

by Lucas Rodriguez Forti, C. Guilherme Becker, Leandro Tacioli, Vânia Rosa Pereira, André Cid F. A. Santos, Igor Oliveira, Célio F. B. Haddad, Luís Felipe Toledo Introduced species have the potential to become invasive and jeopardize entire ecosystems. The success of species establishing viable populations outside their original extent depends primarily on favorable climatic conditions in the invasive ranges. Species distribution modeling (SDM) can thus be used to estimate potential habitat suitability for populations of invasive species. Here we review the status of six amphibian species with invasive populations in Brazil (four domestic species and two imported species). We (i) modeled the current habitat suitability and future potential distribution of these six focal species, (ii) reported on the disease status of Eleutherodactylus johnstonei and Phyllodytes luteolus , and (iii) quantified the acoustic overlap of P . luteolus and Leptodactylus labyrinthicus with three co-o ...

by Maryam Shahdoust, Hamid Pezeshk, Hossein Mahjub, Mehdi Sadeghi The Common topological features of related species gene regulatory networks suggest reconstruction of the network of one species by using the further information from gene expressions profile of related species. We present an algorithm to reconstruct the gene regulatory network named; F-MAP, which applies the knowledge about gene interactions from related species. Our algorithm sets a Bayesian framework to estimate the precision matrix of one species microarray gene expressions dataset to infer the Gaussian Graphical model of the network. The conjugate Wishart prior is used and the information from related species is applied to estimate the hyperparameters of the prior distribution by using the factor analysis. Applying the proposed algorithm on six related species of drosophila shows that the precision of reconstructed networks is improved considerably compared to the precision of networks constructed by other Bayesian ...

by QingJun Song, HaiYan Jiang, Qinghui Song, XieGuang Zhao, Xiaoxuan Wu Top-coal caving technology is a productive and efficient method in modern mechanized coal mining, the study of coal-rock recognition is key to realizing automation in comprehensive mechanized coal mining. In this paper we propose a new discriminant analysis framework for coal-rock recognition. In the framework, a data acquisition model with vibration and acoustic signals is designed and the caving dataset with 10 feature variables and three classes is got. And the perfect combination of feature variables can be automatically decided by using the multi-class F-score (MF-Score) feature selection. In terms of nonlinear mapping in real-world optimization problem, an effective minimum enclosing ball (MEB) algorithm plus Support vector machine (SVM) is proposed for rapid detection of coal-rock in the caving process. In particular, we illustrate how to construct MEB-SVM classifier in coal-rock recognition which exhibit i ...

by Genevieve Rocheleau, Conrado Franco-Villalobos, Natalia Oliveira, Zabrina L. Brumme, Melanie Rusch, Jeannie Shoveller, Chanson J. Brumme, P. Richard Harrigan Sociodemographic correlates of engagement in human immunodeficiency virus (HIV) care are well studied, however the association with accessing drug resistance testing (DRT) and the development of drug resistance have not been characterized. Between 19962014, 11 801 HIV patients accessing therapy in British Columbia were observed longitudinally. A subset of 9456 patients had testable viral load; of these 8398 were linked to census data. Sociodemographic (census tract-level) and clinical (individual-level) correlates of DRT were assessed using multivariable General Estimating Equation logistic regression adjusted odds ratios (aOR). The mean number of tests per patient was 2.1 (Q1-Q3; 03). Separately, any drug resistance was determined using IAS-USA (2013) list for 5703 initially treatment naïve patients without baseline resista ...