リンク集 RSS/ATOM 記事

by Jinming Du Global cooperation is urgently needed to prevent risks of world-wide extreme events and disasters for sustainable development. In human societies, however, there exists bias toward interacting with partners with similar characteristics, but not contributing globally. We study how complex interactive behaviors evolve under risks through proposing a threshold public goods game model. In the model, individuals either play games with participants who own the same phenotype, or contribute to the collective target of global public goods. We further introduce an insurance compensation mechanism into the model to probe the evolution of global cooperation. It is found that the introduction of the insurance remarkably promotes the emergence of global cooperative behavior and inhibits the tendency to play games only with individuals of the same phenotype. Besides, contrary to models without insurance, global cooperation is strengthened with the increase of imitation intensities. In ...

by Mari Kemppainen, Anna-Maria Lahesmaa-Korpinen, Paula Kauppi, Martti Virtanen, Suvi M. Virtanen, Riitta Karikoski, Mika Gissler, Turkka Kirjavainen Background Asthma is the most common chronic disease during pregnancy and it may have influence on pregnancy outcome. Objectives Our goal was to assess the association between maternal asthma and the perinatal risks as well as possible effects of asthma medication. Methods The study was based on a nationwide Finnish register-based cohort between the years 1996 and 2012 in the Drug and Pregnancy Database. The register data comprised 962 405 singleton live and stillbirths, 898 333 (93.3%) pregnancies in mothers with neither confirmed asthma nor use of asthma medication (controls), and 26 674 (2.8%) pregnancies with confirmed maternal asthma. 71% of mothers with asthma used asthma medication. The diagnosis of asthma was based on the mothers’ right for subsidised medication which is carefully evaluated by strict criteria including pulmonar ...

by Keith Bouma-Gregson, Raphael M. Kudela, Mary E. Power Benthic algae fuel summer food webs in many sunlit rivers, and are hotspots for primary and secondary production and biogeochemical cycling. Concerningly, riverine benthic algal assemblages can become dominated by toxic cyanobacteria, threatening water quality and public health. In the Eel River in Northern California, over a dozen dog deaths have been attributed to cyanotoxin poisonings since 2000. During the summers of 2013–2015, we documented spatial and temporal patterns of cyanotoxin concentrations in the watershed, showing widespread distribution of anatoxin-a in benthic cyanobacterial mats. Solid phase adsorption toxin tracking (SPATT) samplers were deployed weekly to record dissolved microcystin and anatoxin-a levels at 10 sites throughout the watershed, and 187 Anabaena -dominated or Phormidium- dominated cyanobacterial mat samples were collected from 27 locations to measure intracellular anatoxin-a (ATX) and microcys ...

by Christopher A. Drummond, Xiaoming Fan, Steven T. Haller, David J. Kennedy, Jiang Liu, Jiang Tian The Na/K-ATPase is an important membrane ion transporter and a signaling receptor that is essential for maintaining normal cell function. The current study examined the role of Na/K-ATPase signaling in regulating miR-29b-3p, an anti-fibrotic microRNA, in a mouse chronic kidney disease (CKD) model (5/6 th partial nephrectomy or PNx). The results showed that CKD induced significant reduction of miR-29b-3p expression in the heart tissue by activation of Src and NFκB signaling in these animals. To demonstrate the role of Na/K-ATPase signaling, we also performed the PNx surgery on Na/K-ATPase α1 heterozygous (α1+/-) mice, which expresses ~40% less Na/K-ATPase α1 compared to their wild type littermates (WT) and exhibits deficiency in Na/K-ATPase signaling. We found that CKD did not significantly change the miR-29b-3p expression in heart tissue from the α1+/- animals. We also found that C ...

Malaysia probe into 1MDB heats up with live-streamed police operations

Platform tones down some Eurosceptic rhetoric but steps up curbs on migration

With dozens dead in the worst clashes for years, regional powers are trying to halt the violence between Israel and the Palestinian enclave

Attempt to save nuclear deal with Tehran by allowing companies to ignore embargo

Acquisition was one of the most profitable private equity deals ever

Five Star and League strike deal to govern country that feeds eurozone instability